INTRAOCULAR PRESSURE LOWERING ACTIVITY OF JASMINUM AURICULATUM IN EXPERIMENTAL ANIMALS INDUCED GLAUCOMA
P. Hasanthi Lakshmi 1, H.G. Raghavendra2, Department of Pharmacology, CES College of pharmacy, Kurnool.
DOI : https://doi.org/10.63712/bpsrj-v1i1p002
KEYWORDS:
Glaucoma, JAEE (JASMINUM AURICULATUM Ethanolic Extract), SOD, Glutamate.
ABSTRACT:
Glaucoma termed as a cluster of heterogenous disorders that cause blindness due to damage of cells in retinal ganglionic region and harm to the nerves present in optic region. It leads to loss of vision and isual impairment widely throughout world. There are several medications currently available for glaucoma treatment but have certain drawbacks. From the phytochemical screening ethanolic extract of JASMINUM AURICULATUM contains glycosides, alkaloids, tannins, steroids, educing sugars, saponins and terpenoids. The brief outcomes of the current study in JAEE administered rabbits pretreated with water and steroids shown decrease in IOP and show decrease in glutamate and increase in catalase and SOD antioxidant parameters compared to disease and normal control groups.